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Mention “cirrhosis” and it typically conjurs an immediate association with excessive alcohol consumption. But although this connection is well established, it’s not the end of the story.
The full spectrum of so-called “fatty liver diseases” that interfere with the liver’s normal metabolism of fat and lead to cirrhosis, are also increasingly recognised as occurring in individuals who are overweight or obese, or have type 2 diabetes.
In his Inaugural Lecture, Professor Alastair Burt describes this disease spectrum and the importance of accurate diagnosis, both for individuals and in epidemiological studies and clinical trials.
He also considers factors that may influence individual susceptibility to advanced disease, and emerging novel treatments.