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Underactive Thyroid Symptoms. Part of the series: Medical Symptoms, Causes & Treatments. Underactive thyroid symptoms include feeling sluggish, tiredness, weight gain, cold sensitivity and pale, dry skin. Discover more symptoms of hypothyroidism, such as memory loss, problems with menstrual cycles and decreased respiratory rate, with information from a nurse and respiratory care practitioner in this free video on underactive thyroid symptoms. Read more: